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Tuesday, April 27, 2010

Management of neuroendocrine tumour (NET)

Neuroendocfine tumor are a relatively rare group of tumour .The incidence and the prevalence has been increasing over the year .This probably is due to increase awareness among the medical professionals and the pathologist .The spectrum of clinical and histological grading vary widely .The prognosis varies widely depending on number of factors
age
load of disease
site of disease liver only Vs other ares
symptom
Performance status (is patient active)etc

There are number of management option .So it should be ,managed with multidisciplinary team .
1-surgery
2-chemotherapy
Cisplatin
etoposide
streptozocin
capecitabine
Temozolamaide
5-FU
Doxorubicin etc in combination
3-Radioembolisation (blocking segment of liver with cancer with beads)
4-Lutetium and other PRRT treatment - available in Europe ,part of Australia
5-symptom control with somatostatin analogue (some evidence it has anti cancer effect)
6- clinical trial
Sunitinib
everolumus

For patients being investigated for cancer unknown primary -- please check with your doctor if this might be NET

seek opinion from centres which deals with these cancer .
Erasmus University Medical Center, Rotterdam (The Netherlands)
Uppsala University Hospital, Sweden
Bad Berka Germany

useful website
Carcinoid.org
Unicorn foundation australia


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